Almonertinib (hydrochloride), CAS [[2134096-03-8]]

Produktübersicht

• Artikelname: Almonertinib (hydrochloride), CAS [[2134096-03-8]]
• Artikelnummer: MCE-HY-112823B
• Hersteller Artikelnummer: HY-112823B
• Alternativnummer: MCE-HY-112823B-100MG,MCE-HY-112823B-50MG,MCE-HY-112823B-25MG,MCE-HY-112823B-5MG,MCE-HY-112823B-10MG,MCE-HY-112823B-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: HS-10296 (hydrochloride)

Produktbeschreibung

Almonertinib (HS-10296) hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib hydrochloride shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib hydrochloride is used for the research of the non-small cell lung cancer[1][2].

Produkteigenschaften

• Molekulargewicht: 562.11
• Reinheit: 98.92
• CAS Nummer: [2134096-03-8]
• Formel: C30H36ClN7O2
• Target-Kategorie: EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound