Almonertinib (hydrochloride), CAS [[2134096-03-8]]

Product Overview

• Article Name: Almonertinib (hydrochloride), CAS [[2134096-03-8]]
• Biozol Catalog Number: MCE-HY-112823B
• Supplier Catalog Number: HY-112823B
• Alternative Catalog Number: MCE-HY-112823B-100MG,MCE-HY-112823B-50MG,MCE-HY-112823B-25MG,MCE-HY-112823B-5MG,MCE-HY-112823B-10MG,MCE-HY-112823B-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: HS-10296 (hydrochloride)

Product Description

Almonertinib (HS-10296) hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib hydrochloride shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib hydrochloride is used for the research of the non-small cell lung cancer[1][2].

Product Properties

• Molecular Weight: 562.11
• Purity: 98.92
• CAS Number: [2134096-03-8]
• Formula: C30H36ClN7O2
• Target: EGFR

Application Notes

• Application Notes: MCE Product type: Reference compound