D-alpha-Hydroxyglutaric acid, CAS [[13095-47-1]]

Produktübersicht

• Artikelname: D-alpha-Hydroxyglutaric acid, CAS [[13095-47-1]]
• Artikelnummer: MCE-HY-113038
• Hersteller Artikelnummer: HY-113038
• Alternativnummer: MCE-HY-113038-100MG,MCE-HY-113038-10MMX1ML,MCE-HY-113038-10MG,MCE-HY-113038-50MG,MCE-HY-113038-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (R)-2-Hydroxyglutarate, (R)-2-Hydroxyglutaric acid, (R)-2-Hydroxypentanedioic acid

Produktbeschreibung

D-alpha-Hydroxyglutaric acid ((R)-2-Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-alpha-Hydroxyglutaric acid is a weak competitive antagonist of alpha-ketoglutarate (alpha-KG) and inhibits multiple alpha-KG-dependent dioxygenases with a Ki of 10.87 mM. D-alpha-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-alpha-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 148.11
• Reinheit: 98
• CAS Nummer: [13095-47-1]
• Formel: C5H8O5
• Target-Kategorie: ATP Synthase,Endogenous Metabolite,mTOR,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products