D-alpha-Hydroxyglutaric acid, CAS [[13095-47-1]]

Product Overview

• Article Name: D-alpha-Hydroxyglutaric acid, CAS [[13095-47-1]]
• Biozol Catalog Number: MCE-HY-113038
• Supplier Catalog Number: HY-113038
• Alternative Catalog Number: MCE-HY-113038-10MMX1ML,MCE-HY-113038-100MG,MCE-HY-113038-50MG,MCE-HY-113038-25MG,MCE-HY-113038-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (R)-2-Hydroxyglutarate, (R)-2-Hydroxyglutaric acid, (R)-2-Hydroxypentanedioic acid

Product Description

D-alpha-Hydroxyglutaric acid ((R)-2-Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-alpha-Hydroxyglutaric acid is a weak competitive antagonist of alpha-ketoglutarate (alpha-KG) and inhibits multiple alpha-KG-dependent dioxygenases with a Ki of 10.87 mM. D-alpha-Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D-alpha-Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling[1][2][3][4][5].

Product Properties

• Molecular Weight: 148.11
• Purity: 98
• CAS Number: [13095-47-1]
• Formula: C5H8O5
• Target: ATP Synthase,Endogenous Metabolite,mTOR,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: Natural Products