15-keto-Prostaglandin F2a (15-keto-PGF2alpha) is a key oxidative metabolite of the primary prostaglandin PGF2alpha in vivo. The prostaglandin receptor agonist activity of 15-keto-Prostaglandin F2a itself is significantly attenuated. 15-keto-Prostaglandin F2a acts as a pro-inflammatory lipid mediator that potently binds to OPG, RANKL and TRAF6, and its level is significantly elevated in the serum of collagen-induced arthritis mice. 15-keto-Prostaglandin F2a can be used for the study of rheumatoid arthritis[1].
Molekulargewicht:
352.47
Reinheit:
99.2
CAS Nummer:
[35850-13-6]
Formel:
C20H32O5
Target-Kategorie:
Endogenous Metabolite,RANKL/RANK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten