7-Ketocholesterol is an oxidation product of cholesterol, widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol. 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7alpha-hydroxylase and HMG-CoA reductase. 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis (apoptosis)[1].
Molekulargewicht:
400.64
Reinheit:
99.87
CAS Nummer:
[566-28-9]
Formel:
C27H44O2
Target-Kategorie:
Endogenous Metabolite,p38 MAPK
Anwendungsbeschreibung:
MCE Product type: Natural Products
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