7-Ketocholesterol is an oxidation product of cholesterol, widely present in atherosclerotic plaques, and has a stronger atherogenic effect than cholesterol. 7-Ketocholesterol can inhibit the rate-limiting enzymes involved in bile acid and cholesterol synthesis, such as cholesterol 7alpha-hydroxylase and HMG-CoA reductase. 7-Ketocholesterol exhibits pro-inflammatory effects both in vivo and in vitro and can induce cell apoptosis (apoptosis)[1].
Molecular Weight:
400.64
Purity:
99.87
CAS Number:
[566-28-9]
Formula:
C27H44O2
Target:
Endogenous Metabolite,p38 MAPK
Application Notes:
MCE Product type: Natural Products
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