Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells[1].
Molekulargewicht:
478.62
Reinheit:
98
CAS Nummer:
[2082752-83-6]
Formel:
C26H42N2O6
Target-Kategorie:
MetAP
Anwendungsbeschreibung:
MCE Product type: Reference compound
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