Aclimostat (ZGN-1061) is a potent inhibitor of the MetAP2 enzyme and displays favorable efficacy and safety in preclinical studies. ZGN-1061 produced similar efficacy as beloranib for weight loss, improvements in metabolic parameters in a mouse model of obesity and insulin resistance, and concordant changes in gene transcription in HepG2 cells[1].
Molecular Weight:
478.62
Purity:
98
CAS Number:
[2082752-83-6]
Formula:
C26H42N2O6
Target:
MetAP
Application Notes:
Reference compound
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