MD-224, CAS [[2136247-12-4]]

Produktübersicht

• Artikelname: MD-224, CAS [[2136247-12-4]]
• Artikelnummer: MCE-HY-114312
• Hersteller Artikelnummer: HY-114312
• Alternativnummer: MCE-HY-114312-500MG,MCE-HY-114312-10MMX1ML,MCE-HY-114312-250MG,MCE-HY-114312-5MG,MCE-HY-114312-25MG,MCE-HY-114312-100MG,MCE-HY-114312-50MG,MCE-HY-114312-10MG,MCE-HY-114312-1G
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 consists of ligands for Cereblon and MDM2. MD-224 induces rapid degradation of MDM2 at concentrations IC50 value of 1.5 nM in inhibition of growth of RS4,11 cells. MD-224 has the potential to be a new class of anticancer agent[1]. MD-224 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Produkteigenschaften

• Molekulargewicht: 889.80
• Reinheit: 99.60
• CAS Nummer: [2136247-12-4]
• Formel: C48H43Cl2FN6O6
• Target-Kategorie: E1/E2/E3 Enzyme,MDM-2/p53,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound