PROTAC FLT-3 degrader 1 is an effective and selective FLT-3 PROTAC degrader with an IC50 of 0.6 nM. PROTAC FLT-3 degrader 1 inhibits both FLT-3 and FLT-3 ITD mutants. PROTAC FLT-3 degrader 1 has the activity of anti-proliferation and induction of apoptosis, which can be used in the study of tumor. (Pink: FLT3 ligand (HY-168702), Black: Linker (HY-124380), Blue: VHL ligand (HY-125845))[1].
Molekulargewicht:
1020.23
Reinheit:
99.74
CAS Nummer:
[2230826-81-8]
Formel:
C52H61N9O9S2
Target-Kategorie:
Apoptosis,ERK,FLT3,MEK,PROTACs,STAT
Anwendungsbeschreibung:
MCE Product type: Reference compound
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