GNE-8505, CAS [[1620573-48-9]]

Produktübersicht

• Artikelname: GNE-8505, CAS [[1620573-48-9]]
• Artikelnummer: MCE-HY-114332
• Hersteller Artikelnummer: HY-114332
• Alternativnummer: MCE-HY-114332-5MG,MCE-HY-114332-10MMX1ML,MCE-HY-114332-1MG,MCE-HY-114332-10MG,MCE-HY-114332-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GNE-8505 is an orally active, blood-brain barrier-permeable selective dual leucine zipper kinase (DLK) inhibitor. GNE-8505 inhibits the DLK/JNK pathway, reduces stress-induced c-Jun phosphorylation levels, decreases neuronal death and suppresses axonal degeneration. GNE-8505 reduces phosphorylated c-Jun levels in the retina, spinal cord and brain tissues of mice. GNE-8505 is applicable to research related to Alzheimers disease and amyotrophic lateral sclerosis (ALS)[1].

Produkteigenschaften

• Molekulargewicht: 419.44
• Reinheit: 99.53
• CAS Nummer: [1620573-48-9]
• Formel: C21H24F3N5O
• Target-Kategorie: JNK,MAP3K

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound