DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo[1].
Molekulargewicht:
735.80
Reinheit:
99.92
CAS Nummer:
[1855860-24-0]
Formel:
C41H42FN5O7
Target-Kategorie:
c-Met/HGFR,TAM Receptor,Trk Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten