TNF-alpha-IN-19 is an inhibitor of TNFalpha that can block the interaction between TNFalphaRI, TRADD, and RIP1, the EC50 values for TNFalpha, IL-1beta, and IL-1beta/TNFalpha are 2.451, 3.792 and 1.54 µM, respectively. TNF-alpha-IN-19 only inhibits the degradation of IkappaBalpha when cells are stimulated by TNFalpha and not by IL-1beta[1].
Molekulargewicht:
348.71
CAS Nummer:
[338773-13-0]
Formel:
C16H8ClF3N4
Target-Kategorie:
IKK,Interleukin Related,RIP kinase,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten