AFN-1252 (tosylate), CAS [[1047981-31-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-114622
Hersteller Artikelnummer:
HY-114622
Alternativnummer:
MCE-HY-114622-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
API-1252 (tosylate), Debio 1452 (tosylate)
AFN-1252 (API-1252) tosylate is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 tosylate exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 tosylate exhibits typical MIC90 values of 0.015 µg/ml against diverse clinical isolates of S. aureus. AFN-1252 tosylate is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith[1][2].
Molekulargewicht:
547.62
CAS Nummer:
[1047981-31-6]
Formel:
C29H29N3O6S
Target-Kategorie:
Antibiotic,Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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