AFN-1252 (tosylate), CAS [[1047981-31-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-114622
Supplier Catalog Number:
HY-114622
Alternative Catalog Number:
MCE-HY-114622-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
API-1252 (tosylate), Debio 1452 (tosylate)
AFN-1252 (API-1252) tosylate is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 tosylate exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 tosylate exhibits typical MIC90 values of 0.015 µg/ml against diverse clinical isolates of S. aureus. AFN-1252 tosylate is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith[1][2].
Molecular Weight:
547.62
CAS Number:
[1047981-31-6]
Formula:
C29H29N3O6S
Target:
Antibiotic,Bacterial
Application Notes:
MCE Product type: Reference compound
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