SU-11752 is an inhibitor for DNA-dependent protein kinase (DNA-PK) with an IC50 of 0.13 µM. SU-11752 inhibits PI3K p110gamma kinase with IC50 of 1.1 µM. SU-11752 binds competitively for ATP-site in DNA-PK, results in inhibition of intracellular DNA double-strand break repair and increases the sensitivity of cells to radiotherapy[1].
Molekulargewicht:
493.57
CAS Nummer:
[688036-19-3]
Formel:
C26H27N3O5S
Target-Kategorie:
DNA-PK,PI3K
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
