SU-11752 is an inhibitor for DNA-dependent protein kinase (DNA-PK) with an IC50 of 0.13 µM. SU-11752 inhibits PI3K p110gamma kinase with IC50 of 1.1 µM. SU-11752 binds competitively for ATP-site in DNA-PK, results in inhibition of intracellular DNA double-strand break repair and increases the sensitivity of cells to radiotherapy[1].
Molecular Weight:
493.57
CAS Number:
[688036-19-3]
Formula:
C26H27N3O5S
Target:
DNA-PK,PI3K
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
