Lenalidomide-C4-NH2 (hydrochloride), CAS [[2435715-90-3]]

Produktübersicht

• Artikelname: Lenalidomide-C4-NH2 (hydrochloride), CAS [[2435715-90-3]]
• Artikelnummer: MCE-HY-115446A
• Hersteller Artikelnummer: HY-115446A
• Alternativnummer: MCE-HY-115446A-100MG,MCE-HY-115446A-10MG,MCE-HY-115446A-500MG,MCE-HY-115446A-25MG,MCE-HY-115446A-50MG,MCE-HY-115446A-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Cereblon ligand 1 (hydrochloride), E3 ligase Ligand-Linker Conjugates 32 (hydrochloride)

Produktbeschreibung

Lenalidomide-C4-NH2 hydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C4-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC (Compound 24), which has IC50s of 0.98 nM and 13.7 nM in inhibition of RS4,11 and MOLM-13 acute leukemia cell lines growth, respectively[1].

Produkteigenschaften

• Molekulargewicht: 351.83
• Reinheit: 98.85
• CAS Nummer: [2435715-90-3]
• Formel: C17H22ClN3O3
• Target-Kategorie: E3 Ligase Ligand-Linker Conjugates

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1