GW406108X, CAS [[1644443-92-4]]

Produktübersicht

• Artikelname: GW406108X, CAS [[1644443-92-4]]
• Artikelnummer: MCE-HY-115570
• Hersteller Artikelnummer: HY-115570
• Alternativnummer: MCE-HY-115570-10MG,MCE-HY-115570-10MMX1ML,MCE-HY-115570-100MG,MCE-HY-115570-25MG,MCE-HY-115570-5MG,MCE-HY-115570-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: GW108X

Produktbeschreibung

GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK[1][2].

Produkteigenschaften

• Molekulargewicht: 400.21
• Reinheit: 98
• CAS Nummer: [1644443-92-4]
• Formel: C20H11Cl2NO4
• Target-Kategorie: Autophagy,Kinesin,ULK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound