AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.
Molekulargewicht:
477.59
CAS Nummer:
[74480-23-2]
Formel:
C29H35NO5
Target-Kategorie:
Prostaglandin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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