AH22921 is an EP4 prostaglandin receptor antagonist with the activity of antagonizing the activation of adenylate cyclase by prostaglandins in CHO cells. AH22921 can shift the PGE2 concentration-response curve to the right in CHO cells. It is a non-competitive antagonist that is selective for EP4 receptors and has an antagonistic effect on EP4 receptors in CHO cells, but does not affect the PGE2 concentration-response curve in NPE cells containing EP2 receptors.
Molecular Weight:
477.59
CAS Number:
[74480-23-2]
Formula:
C29H35NO5
Target:
Prostaglandin Receptor
Application Notes:
MCE Product type: Reference compound1
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