SHP2-IN-9 is a specific SHP2 inhibitor (IC50 =1.174 µM) with enhanced blood-brain barrier penetration. SHP2-IN-9 shows 85-fold more selective for SHP2 than SHP1. SHP2-IN-9 inhibits SHP2-mediated cell signal transduction and cancer cell proliferation, and inhibits the growth of cervix cancer tumors and glioblastoma growth in vivo[1].
Molekulargewicht:
385.46
Reinheit:
98.80
CAS Nummer:
[2987135-92-0]
Formel:
C20H20FN3O2S
Target-Kategorie:
Phosphatase,SHP2
Anwendungsbeschreibung:
MCE Product type: Reference compound
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