SHP2-IN-9 is a specific SHP2 inhibitor (IC50 =1.174 µM) with enhanced blood-brain barrier penetration. SHP2-IN-9 shows 85-fold more selective for SHP2 than SHP1. SHP2-IN-9 inhibits SHP2-mediated cell signal transduction and cancer cell proliferation, and inhibits the growth of cervix cancer tumors and glioblastoma growth in vivo[1].
Molecular Weight:
385.46
Purity:
98.80
CAS Number:
[2987135-92-0]
Formula:
C20H20FN3O2S
Target:
Phosphatase,SHP2
Application Notes:
MCE Product type: Reference compound
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