GRPR antagonist-1 is a potent gastrin releasing peptide receptor (GRPR) antagonist, having the cytotoxicity against certain cancer cells (IC50 of 4.97, 4.36 and 3.40 µM in PC3, Pan02 and HGC-27 cells, respectively). GRPR antagonist-1 inhibits HGC-27 cell viability by decreasing the Bcl-2 level and increasing the Bax level, causing apoptosis, with anticancer activity[1].
Molekulargewicht:
558.59
Reinheit:
99.80
CAS Nummer:
[3052544-28-9]
Formel:
C29H33F3N4O4
Target-Kategorie:
Bombesin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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