(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (µ-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury[1].
Molekulargewicht:
482.57
Reinheit:
99.04
CAS Nummer:
[181769-57-3]
Formel:
C26H34N4O5
Target-Kategorie:
Proteasome
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
