(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (µ-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury[1].
Molecular Weight:
482.57
Purity:
99.04
CAS Number:
[181769-57-3]
Formula:
C26H34N4O5
Target:
Proteasome
Application Notes:
MCE Product type: Reference compound1
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