TASIN-1 (hydrochloride), CAS [[1678515-13-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: TASIN-1 (hydrochloride), CAS [[1678515-13-3]] Preis auf Anfrage
• Artikelnummer: MCE-HY-116572
• Hersteller Artikelnummer: HY-116572
• Alternativnummer: MCE-HY-116572-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TASIN-1 hydrochloride is a selective inhibitor of truncated APCTR (adenomatous polyposis coli gene) that exerts cytotoxic effects by inhibiting cholesterol biosynthesis. TASIN-1 hydrochloride specifically targets colorectal cancer (CRC) cells carrying APC truncated mutations, while having no significant toxicity to wild-type APC cells. TASIN-1 hydrochloride exerts cytotoxic effects by targeting Emopamil binding protein (EBP) to inhibit cholesterol biosynthesis, triggering endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) generation, and JNK-mediated apoptosis, and inhibiting Akt survival signaling. TASIN-1 hydrochloride can be used to prevent and intervene in APC mutant colorectal cancer[1][2][3].

Produkteigenschaften

• Molekulargewicht: 388.95
• CAS Nummer: [1678515-13-3]
• Formel: C18H29ClN2O3S
• Target-Kategorie: Apoptosis,Caspase,JNK,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound