KRCA-0377 is an orally active ALK inhibitor with an IC50 of 0.001 µM. KRCA-0377 also inhibits mutant ALK enzyme with IC50 values 0.01 µM. KRCA-0377 shows cytotoxicity against cancer cells and inhibits tumor growth in xenograft mice models. KRCA-0377 can be used for the research of ALK-positive non-small-cell lung cancer[1].
Molekulargewicht:
488.00
CAS Nummer:
[1845711-03-6]
Formel:
C23H26ClN5O3S
Target-Kategorie:
Anaplastic lymphoma kinase (ALK)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
