TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 passes the blood-brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has beneficial implications for the brain functions of neurogenesis and long-term memory[1].CSP-TTK21 can ameliorate Abeta-impaired long-term potentiation (LTP). CSP-TTK21 may enhance the transcription of genes that promote synaptic health and cognitive function[2]. CSP-TTK21 is orally effective and leads to improvements in motor functions, histone acetylation dynamics in a spinal injury rat model[3].
Molekulargewicht:
357.75
Reinheit:
99.39
CAS Nummer:
[709676-56-2]
Formel:
C17H15ClF3NO2
Target-Kategorie:
Histone Acetyltransferase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
