TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 passes the blood-brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has beneficial implications for the brain functions of neurogenesis and long-term memory[1].CSP-TTK21 can ameliorate Abeta-impaired long-term potentiation (LTP). CSP-TTK21 may enhance the transcription of genes that promote synaptic health and cognitive function[2]. CSP-TTK21 is orally effective and leads to improvements in motor functions, histone acetylation dynamics in a spinal injury rat model[3].
Molecular Weight:
357.75
Purity:
99.39
CAS Number:
[709676-56-2]
Formula:
C17H15ClF3NO2
Target:
Histone Acetyltransferase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
