PIN1 inhibitor API-1, CAS [[680622-70-2]]

Produktübersicht

• Artikelname: PIN1 inhibitor API-1, CAS [[680622-70-2]]
• Artikelnummer: MCE-HY-116716
• Hersteller Artikelnummer: HY-116716
• Alternativnummer: MCE-HY-116716-10MG,MCE-HY-116716-25MG,MCE-HY-116716-100MG,MCE-HY-116716-50MG,MCE-HY-116716-5MG,MCE-HY-116716-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor (API-1) with an IC50 of 72.3 nM. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase (PPIase) domain and potently inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development[1].

Produkteigenschaften

• Molekulargewicht: 366.30
• Reinheit: 99.63
• CAS Nummer: [680622-70-2]
• Formel: C15H13F3N6O2
• Target-Kategorie: MicroRNA

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound