Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3beta and CDK-5 with IC50s of 10.2 µM and 1.5 µM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1[1][2][3][4].
Molekulargewicht:
548.76
Reinheit:
98.2
CAS Nummer:
[104196-68-1]
Formel:
C36H44N4O
Target-Kategorie:
Autophagy,CDK,GSK-3,HSV,Parasite,Proton Pump
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
