4-trans-Hydroxy-glibenclamide, CAS [[23155-00-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: 4-trans-Hydroxy-glibenclamide, CAS [[23155-00-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-117160
• Hersteller Artikelnummer: HY-117160
• Alternativnummer: MCE-HY-117160-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 4-trans-hydroxycyclohexyl Glyburide, 4-trans-hydroxy Glibenclamide

Produktbeschreibung

rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide (HY-15206). It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9. rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50 values of 0.95 and 100 nM, respectively.

Produkteigenschaften

• Molekulargewicht: 510.00
• Reinheit: 99
• CAS Nummer: [23155-00-2]
• Formel: C23H28ClN3O6S
• Target-Kategorie: Potassium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound