4-trans-Hydroxy-glibenclamide, CAS [[23155-00-2]] Preis auf Anfrage

Product Overview

• Article Name: 4-trans-Hydroxy-glibenclamide, CAS [[23155-00-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-117160
• Supplier Catalog Number: HY-117160
• Alternative Catalog Number: MCE-HY-117160-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: 4-trans-hydroxycyclohexyl Glyburide, 4-trans-hydroxy Glibenclamide

Product Description

rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide (HY-15206). It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9. rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50 values of 0.95 and 100 nM, respectively.

Product Properties

• Molecular Weight: 510.00
• Purity: 99
• CAS Number: [23155-00-2]
• Formula: C23H28ClN3O6S
• Target: Potassium Channel

Application Notes

• Application Notes: MCE Product type: Reference compound