LSP4-2022, CAS [[1413405-33-0]]

Produktübersicht

• Artikelname: LSP4-2022, CAS [[1413405-33-0]]
• Artikelnummer: MCE-HY-117764
• Hersteller Artikelnummer: HY-117764
• Alternativnummer: MCE-HY-117764-5MG,MCE-HY-117764-10MG,MCE-HY-117764-25MG,MCE-HY-117764-50MG,MCE-HY-117764-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

LSP4-2022 is a selective orthosteric mGlu4 receptor agonist with a target EC50 of 0.1 µM and blood-brain barrier permeability.LSP4-2022 activates mGlu4 via interactions with the conserved glutamate binding site and a variable Venus flytrap domain pocket, with no activity at group I and II mGlu receptors and reduced potency at mGlu6, mGlu7, and mGlu8 receptors.LSP4-2022 induces pro-depressant-like effects without altering locomotor activity, inhibits excitatory neurotransmission at parallel fiber-Purkinje cell synapses via presynaptic calcium transient reduction and paired-pulse facilitation increase, and reduces haloperidol-induced catalepsy in rats.LSP4-2022 can be used for the research of depression and parkinsons disease[1][2].

Produkteigenschaften

• Molekulargewicht: 347.26
• Reinheit: 98.06
• CAS Nummer: [1413405-33-0]
• Formel: C13H18NO8P
• Target-Kategorie: mGluR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound