LSP4-2022 is a potent and brain-penetrant mGlu4-selective orthosteric agonist, with an EC50 of 0.11 µM. LSP4-2022 inhibits neurotransmission in cerebellar slices from wild-type but not mGlu4 receptor-knockout mice. LSP4-2022 shows pro-depressant activity[1][2].
Molecular Weight:
347.26
Purity:
98.06
CAS Number:
[1413405-33-0]
Formula:
C13H18NO8P
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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