PF-5177624, CAS [[1350821-45-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: PF-5177624, CAS [[1350821-45-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-117885
• Hersteller Artikelnummer: HY-117885
• Alternativnummer: MCE-HY-117885-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PF-5177624 is a specific and potent inhibitor of PDK1, a key enzyme in the PI3K/AKT signaling pathway that is frequently dysregulated in breast cancer. PDK1 phosphorylates AKT at T308 and other substrates, activating downstream signaling pathways that are important for tumor progression. PF-5177624 blocks IGF-1-stimulated PDK1 activity and downstream AKT and p70S6K phosphorylation, reducing cell proliferation and transformation in breast cancer cells[1].

Produkteigenschaften

• Molekulargewicht: 488.52
• CAS Nummer: [1350821-45-2]
• Formel: C25H25FN8O2
• Target-Kategorie: PDK-1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound