PF-5177624, CAS [[1350821-45-2]] Preis auf Anfrage

Product Overview

• Article Name: PF-5177624, CAS [[1350821-45-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-117885
• Supplier Catalog Number: HY-117885
• Alternative Catalog Number: MCE-HY-117885-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PF-5177624 is a specific and potent inhibitor of PDK1, a key enzyme in the PI3K/AKT signaling pathway that is frequently dysregulated in breast cancer. PDK1 phosphorylates AKT at T308 and other substrates, activating downstream signaling pathways that are important for tumor progression. PF-5177624 blocks IGF-1-stimulated PDK1 activity and downstream AKT and p70S6K phosphorylation, reducing cell proliferation and transformation in breast cancer cells[1].

Product Properties

• Molecular Weight: 488.52
• CAS Number: [1350821-45-2]
• Formula: C25H25FN8O2
• Target: PDK-1

Application Notes

• Application Notes: MCE Product type: Reference compound