RQ-00311651, CAS [[1257116-00-9]] Preis auf Anfrage

Artikelnummer: MCE-HY-118030
Artikelname: RQ-00311651, CAS [[1257116-00-9]] Preis auf Anfrage
Artikelnummer: MCE-HY-118030
Hersteller Artikelnummer: HY-118030
Alternativnummer: MCE-HY-118030-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
RQ-00311651 is a T-type calcium channel blocker that specifically targets the Cav3.2 isoform with a role in neuropathic and visceral pain. RQ-00311651 significantly inhibits T currents in HEK293 cells expressing human Cav3.1 or Cav3.2. RQ-00311651 also inhibited high potassium-induced calcium signaling. RQ-00311651 also inhibits antiallergic properties in rats and mice with neuropathic pain induced by spinal nerve injury or Paclitaxel (HY-B0015). Oral and intraperitoneal injection (10-20 mg/kg) inhibits Cerulein (HY-A0190)-induced acute pancreatitis and cyclophosphamide-induced cystitis in mice[1].
Molekulargewicht: 405.37
CAS Nummer: [1257116-00-9]
Formel: C19H18F3N5O2
Target-Kategorie: Calcium Channel
Anwendungsbeschreibung: MCE Product type: Reference compound