RQ-00311651, CAS [[1257116-00-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-118030
Supplier Catalog Number:
HY-118030
Alternative Catalog Number:
MCE-HY-118030-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
RQ-00311651 is a T-type calcium channel blocker that specifically targets the Cav3.2 isoform with a role in neuropathic and visceral pain. RQ-00311651 significantly inhibits T currents in HEK293 cells expressing human Cav3.1 or Cav3.2. RQ-00311651 also inhibited high potassium-induced calcium signaling. RQ-00311651 also inhibits antiallergic properties in rats and mice with neuropathic pain induced by spinal nerve injury or Paclitaxel (HY-B0015). Oral and intraperitoneal injection (10-20 mg/kg) inhibits Cerulein (HY-A0190)-induced acute pancreatitis and cyclophosphamide-induced cystitis in mice[1].
Molecular Weight:
405.37
CAS Number:
[1257116-00-9]
Formula:
C19H18F3N5O2
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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