PD166326, CAS [[185039-91-2]]

Produktübersicht

• Artikelname: PD166326, CAS [[185039-91-2]]
• Artikelnummer: MCE-HY-118144
• Hersteller Artikelnummer: HY-118144
• Alternativnummer: MCE-HY-118144-100MG,MCE-HY-118144-25MG,MCE-HY-118144-10MG,MCE-HY-118144-5MG,MCE-HY-118144-10MMX1ML,MCE-HY-118144-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PD166326 is an orally active tyrosine kinase inhibitor with a IC50 of 8 nM against abl tyrosine kinase and a IC50 of 6 nM against src tyrosine kinase. PD166326 blocks Bcr/Abl kinase activity. PD166326 inhibits Bcr/Abl-dependent proliferation and cell cycle progression. PD166326 reduces peripheral blood granulocytosis, alleviates splenomegaly and prolongs survival in a mouse model of chronic myeloid leukemia. PD166326 can be used in research related to chronic myeloid leukemia[1][2].

Produkteigenschaften

• Molekulargewicht: 427.28
• Reinheit: 99.99
• CAS Nummer: [185039-91-2]
• Formel: C21H16Cl2N4O2
• Target-Kategorie: Bcr-Abl,p38 MAPK,Src

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound