PD166326, CAS [[185039-91-2]]

Product Overview

• Article Name: PD166326, CAS [[185039-91-2]]
• Biozol Catalog Number: MCE-HY-118144
• Supplier Catalog Number: HY-118144
• Alternative Catalog Number: MCE-HY-118144-100MG,MCE-HY-118144-25MG,MCE-HY-118144-10MG,MCE-HY-118144-5MG,MCE-HY-118144-10MMX1ML,MCE-HY-118144-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PD166326 is an orally active tyrosine kinase inhibitor with a IC50 of 8 nM against abl tyrosine kinase and a IC50 of 6 nM against src tyrosine kinase. PD166326 blocks Bcr/Abl kinase activity. PD166326 inhibits Bcr/Abl-dependent proliferation and cell cycle progression. PD166326 reduces peripheral blood granulocytosis, alleviates splenomegaly and prolongs survival in a mouse model of chronic myeloid leukemia. PD166326 can be used in research related to chronic myeloid leukemia[1][2].

Product Properties

• Molecular Weight: 427.28
• Purity: 99.99
• CAS Number: [185039-91-2]
• Formula: C21H16Cl2N4O2
• Target: Bcr-Abl,p38 MAPK,Src

Application Notes

• Application Notes: MCE Product type: Reference compound