TP0427736 (hydrochloride), CAS [[2459963-17-6]]

Produktübersicht

• Artikelname: TP0427736 (hydrochloride), CAS [[2459963-17-6]]
• Artikelnummer: MCE-HY-118528A
• Hersteller Artikelnummer: HY-118528A
• Alternativnummer: MCE-HY-118528A-5MG,MCE-HY-118528A-50MG,MCE-HY-118528A-10MG,MCE-HY-118528A-25MG,MCE-HY-118528A-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

TP0427736 hydrochloride is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50=836 nM). TP0427736 hydrochloride also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-beta1 with an IC50 value of 8.68 nM. TP0427736 hydrochloride can be used for the research of androgenic alopecia (AGA)[1].

Produkteigenschaften

• Molekulargewicht: 334.85
• Reinheit: 99.22
• CAS Nummer: [2459963-17-6]
• Formel: C14H11ClN4S2
• Target-Kategorie: TGF-beta Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound