Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin-1 is a potent and selective PIKfyve inhibitor and inhibits late-stage autophagy by impairing lysosomal maturation. Vacuolin-1 can induce vacuole formation and increase the percentage of enucleated cells[1][2][4].
Molekulargewicht:
577.42
Reinheit:
98.54
CAS Nummer:
[351986-85-1]
Formel:
C26H24IN7O
Target-Kategorie:
Autophagy,PIKfyve
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
