CU239 is a potent and competitive non-retinoic acid inhibitor of RPE65 with an IC50 for RPE65 isomerase (11-cis retinal) of 6 µM. CCU239 exhibits delayed chromophore regeneration after light bleach, and conferrs a partial protection of the retina against injury from high intensity light. CU239 can be used for the study of retinal degeneration[1].
Molekulargewicht:
436.41
CAS Nummer:
[946249-82-7]
Formel:
C19H15F3N4O3S
Target-Kategorie:
RPE65
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
