CU239 is a potent and competitive non-retinoic acid inhibitor of RPE65 with an IC50 for RPE65 isomerase (11-cis retinal) of 6 µM. CCU239 exhibits delayed chromophore regeneration after light bleach, and conferrs a partial protection of the retina against injury from high intensity light. CU239 can be used for the study of retinal degeneration[1].
Molecular Weight:
436.41
CAS Number:
[946249-82-7]
Formula:
C19H15F3N4O3S
Target:
RPE65
Application Notes:
MCE Product type: Reference compound
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