Medifoxamine is an orally active monoamine reuptake inhibitor and antidepressant. Medifoxamine preferentially inhibits presynaptic dopamine reuptake. Medifoxamine acts as an intraocular pressure-lowering agent to reduce intraocular pressure, and also functions as a miotic agent to decrease pupil diameter. Medifoxamine exhibits characteristic properties of antidepressant compounds, including preventing hypothermia induced by Reserpine (HY-N0480) or Apomorphine (HY-12723), potentiating the toxic effects of Yohimbine (HY-N0127) in mice, and reducing immobility behavior in mice and rats in the behavioral despair model. Medifoxamine has no anticholinergic activity. Medifoxamine can be used in research related to depression[1][2].
Molekulargewicht:
257.33
Reinheit:
99.34
CAS Nummer:
[32359-34-5]
Formel:
C16H19NO2
Target-Kategorie:
Dopamine Transporter
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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