Medifoxamine is an orally active monoamine reuptake inhibitor and antidepressant. Medifoxamine preferentially inhibits presynaptic dopamine reuptake. Medifoxamine acts as an intraocular pressure-lowering agent to reduce intraocular pressure, and also functions as a miotic agent to decrease pupil diameter. Medifoxamine exhibits characteristic properties of antidepressant compounds, including preventing hypothermia induced by Reserpine (HY-N0480) or Apomorphine (HY-12723), potentiating the toxic effects of Yohimbine (HY-N0127) in mice, and reducing immobility behavior in mice and rats in the behavioral despair model. Medifoxamine has no anticholinergic activity. Medifoxamine can be used in research related to depression[1][2].
Molecular Weight:
257.33
Purity:
99.34
CAS Number:
[32359-34-5]
Formula:
C16H19NO2
Target:
Dopamine Transporter
Application Notes:
MCE Product type: Reference compound1
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