AGI-14100, CAS [[1448346-43-7]] Preis auf Anfrage

Artikelnummer: MCE-HY-120181
Artikelname: AGI-14100, CAS [[1448346-43-7]] Preis auf Anfrage
Artikelnummer: MCE-HY-120181
Hersteller Artikelnummer: HY-120181
Alternativnummer: MCE-HY-120181-10MG,MCE-HY-120181-1MG,MCE-HY-120181-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
AGI-14100 is a metabolically stable and orally available mIDH1 inhibitor (IC50=6 nM). The pharmacochemical optimization of AGI-14100 is aimed at eliminating hPXR activation, resulting in the final drug candidate AG-120. AG-120 can be used in the study of cancers carrying IDH1 mutations. The discovery and development of AGI-14100 can be used for further studies of mutant isocitrate dehydrogenase 1 (mIDH1) inhibitors[1].
Molekulargewicht: 599.96
CAS Nummer: [1448346-43-7]
Formel: C29H22ClF4N5O3
Target-Kategorie: Isocitrate Dehydrogenase (IDH)
Anwendungsbeschreibung: MCE Product type: Reference compound